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Aromatic hydrocarbon receptors in mitochondrial biogenesis and function.
Sahebnasagh A, Hashemi J, Khoshi A, Saghafi F, Avan R, Faramarzi F, Azimi S, Habtemariam S, Sureda A, Khayatkashani M, Safdari M, Rezai Ghaleno H, Soltani H, Khayat Kashani HR. Sahebnasagh A, et al. Mitochondrion. 2021 Nov;61:85-101. doi: 10.1016/j.mito.2021.09.012. Epub 2021 Sep 30. Mitochondrion. 2021. PMID: 34600156 Review.
Neutrophil elastase inhibitor (sivelestat) may be a promising therapeutic option for management of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.
Sahebnasagh A, Saghafi F, Safdari M, Khataminia M, Sadremomtaz A, Talaei Z, Rezai Ghaleno H, Bagheri M, Habtemariam S, Avan R. Sahebnasagh A, et al. J Clin Pharm Ther. 2020 Dec;45(6):1515-1519. doi: 10.1111/jcpt.13251. Epub 2020 Aug 28. J Clin Pharm Ther. 2020. PMID: 32860252 Review.
WHAT IS KNOWN AND OBJECTIVE: This article summarizes the effects of sivelestat on acute lung injury/acute respiratory distress syndrome (ALI/ARDS) or ARDS with coagulopathy, both of which are frequently seen in patients with COVID-19. ...Based on its promising beneficial e …
WHAT IS KNOWN AND OBJECTIVE: This article summarizes the effects of sivelestat on acute lung injury/acute respiratory distress syndrome ( …
Chronic alcohol ingestion primes the lung for bleomycin-induced fibrosis in mice.
Sueblinvong V, Kerchberger VE, Saghafi R, Mills ST, Fan X, Guidot DM. Sueblinvong V, et al. Alcohol Clin Exp Res. 2014 Feb;38(2):336-43. doi: 10.1111/acer.12232. Epub 2013 Aug 16. Alcohol Clin Exp Res. 2014. PMID: 24033682 Free PMC article.
BACKGROUND: Alcohol abuse increases the risk for acute lung injury (ALI). In both experimental models and in clinical studies, chronic alcohol ingestion causes airway oxidative stress and glutathione depletion and increases the expression of transforming growth factor beta …
BACKGROUND: Alcohol abuse increases the risk for acute lung injury (ALI). In both experimental models and in clinical studies, chroni …